Tesamorelin

Tesamorelin Overview

Tesamorelin is a stabilized analogue of growth hormone-releasing hormone designed for research involving upstream endocrine signaling. In laboratory settings, it is used to examine how GHRH receptor activity influences pituitary signaling, growth hormone pathway dynamics, and broader hormone-regulated cellular processes.

Mechanism of Action & Applications

Tesamorelin is studied for agonist activity at the growth hormone-releasing hormone receptor. In research models, this makes it useful for examining pituitary receptor signaling, pulsatile growth hormone pathway activity, hypothalamic-pituitary axis biology, and broader endocrine communication systems. It is commonly used in studies involving GHRH receptor pharmacology, peptide stability, endocrine signaling, and growth hormone pathway regulation.

Research History

Tesamorelin developed from earlier work on native GHRH and shorter GHRH analogues designed to improve stability and preserve receptor activity. As research expanded, tesamorelin became a useful peptide for studying how structural modification can affect peptide half-life, receptor engagement, and downstream endocrine signaling behavior.

Chemical Information

CAS Number

218949-48-5

Molecular Formula

C₂₂₁H₃₆₆N₇₂O₆₇S

Molecular Weight

5,135.9 g/mol

PubChem ID

16137834

Compound

Tesamorelin

Selected quantity

10 MG per vial

Research area

Musculoskeletal & Growth

Intended use

Laboratory research only

Laboratory storage & handling

Form

Lyophilized powder

Short-term

2–8 °C (refrigerated)

Long-term

−20 °C (frozen)

Container

Use the supplied container and follow its label

Lot-specific stability

Not established on this product page

Reconstitution

Consult the applicable research protocol and available lot record

For research use only. Not for human or veterinary use.

The certificate below belongs to Tesamorelin 10 MG, lot P1P-TES10-001. Match the lot number on your vial to the record.

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