Sermorelin

Sermorelin Overview

Sermorelin is a 29-amino-acid analogue of growth hormone-releasing hormone and is widely described as the shortest synthetic fragment that retains the full biologic activity of native GHRH. In research settings, it is used to examine GHRH receptor signaling and how upstream hypothalamic peptide activity influences downstream growth hormone pathway function.

Mechanism of Action & Applications

Sermorelin is studied for agonist activity at the growth hormone-releasing hormone receptor. In laboratory research, this makes it useful for examining pituitary signaling, pulsatile growth hormone release dynamics, receptor activation patterns, and broader endocrine pathway regulation linked to the hypothalamic-pituitary-somatotropic axis.

Research History

Research on sermorelin developed from earlier work on GHRH analogues designed to preserve biologic activity while using a shorter, more defined peptide fragment. Published reviews and earlier comparative studies describe sermorelin as a well-established GHRH analogue used in both endocrine and receptor-signaling research.

Chemical Information

CAS Number

86168-78-7

Molecular Formula

C₁₄₉H₂₄₆N₄₄O₄₂S

Molecular Weight

3,357.9 g/mol

PubChem ID

16132413

Compound

Sermorelin

Selected quantity

10 MG per vial

Research area

Musculoskeletal & Growth

Intended use

Laboratory research only

Laboratory storage & handling

Form

Lyophilized powder

Short-term

2–8 °C (refrigerated)

Long-term

−20 °C (frozen)

Container

Use the supplied container and follow its label

Lot-specific stability

Not established on this product page

Reconstitution

Consult the applicable research protocol and available lot record

For research use only. Not for human or veterinary use.

A certificate for Sermorelin 10 MG has not been published yet. Records are published per lot as they are received; a missing record is not a test result.

Use the lot number on your vial to locate the corresponding certificate once it is available, or contact support for batch documentation.

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