Sermorelin
A 29-amino-acid GHRH analogue studied in growth hormone-releasing research, commonly used to examine somatotropic axis activity in laboratory models. As the shortest fully functional GHRH fragment, it serves as a foundational tool in GH secretion and pituitary signaling studies.
Sermorelin Overview
Sermorelin is a 29-amino-acid analogue of growth hormone-releasing hormone and is widely described as the shortest synthetic fragment that retains the full biologic activity of native GHRH. In research settings, it is used to examine GHRH receptor signaling and how upstream hypothalamic peptide activity influences downstream growth hormone pathway function.
Mechanism of Action & Applications
Sermorelin is studied for agonist activity at the growth hormone-releasing hormone receptor. In laboratory research, this makes it useful for examining pituitary signaling, pulsatile growth hormone release dynamics, receptor activation patterns, and broader endocrine pathway regulation linked to the hypothalamic-pituitary-somatotropic axis.
Research History
Research on sermorelin developed from earlier work on GHRH analogues designed to preserve biologic activity while using a shorter, more defined peptide fragment. Published reviews and earlier comparative studies describe sermorelin as a well-established GHRH analogue used in both endocrine and receptor-signaling research.
Chemical Information
- CAS Number
- 86168-78-7
- Molecular Formula
- C149H246N44O42S
- Molecular Weight
- 3,357.9 g/mol
- PubChem ID
- 16132413
For research use only. Not for human or veterinary use. Detailed storage guidelines →
Often Paired With
Researchers who buy Sermorelin commonly stock these alongside it.
Researcher Reviews
