5-Amino-1MQ

5-Amino-1MQ Overview

5-Amino-1MQ is a quinolinium-based small molecule studied in metabolic research involving NNMT, an enzyme that uses nicotinamide as a substrate in methylation-related biochemical processes. In laboratory settings, it is used to examine how NNMT activity affects cellular energy metabolism, NAD+-linked biology, and broader metabolic signaling.

Mechanism of Action & Applications

5-Amino-1MQ is studied as an NNMT inhibitor. In research models, this makes it useful for examining how reduced NNMT activity changes intracellular nicotinamide handling, methyl donor utilization, and downstream metabolic signaling. It is commonly used in studies involving cellular metabolism, NAD+-associated pathways, adipocyte biology, and enzyme-driven metabolic regulation.

Research History

Research interest in 5-Amino-1MQ grew from broader efforts to understand NNMT as a regulator of metabolic and epigenetic biology. Published work has described 5-Amino-1MQ as a selective, cell-permeable small-molecule NNMT inhibitor and has used it in controlled models to study enzyme inhibition, metabolic pathway changes, and related cellular responses.

Chemical Information

CAS Number

42464-96-0Chemical Name: 5-Amino-1-methylquinolinium iodide

Molecular Formula

C₁₀H₁₁IN₂

Molecular Weight

286.11 g/mol

Compound

5-Amino-1MQ

Selected quantity

50 MG per vial

Research area

Metabolic & Endocrine

Intended use

Laboratory research only

Laboratory storage & handling

Form

Lyophilized powder

Short-term

2–8 °C (refrigerated)

Long-term

−20 °C (frozen)

Container

Use the supplied container and follow its label

Lot-specific stability

Not established on this product page

Reconstitution

Consult the applicable research protocol and available lot record

For research use only. Not for human or veterinary use.

A certificate for 5-Amino-1MQ 50 MG has not been published yet. Records are published per lot as they are received; a missing record is not a test result.

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