CJC-1295 (No DAC)

CJC-1295 (No DAC) Overview

CJC-1295 (No DAC), also commonly referred to as Modified GRF (1-29), is a GHRH-based peptide analogue studied for its activity at the growth hormone-releasing hormone receptor. Unlike the DAC version, it does not include the drug affinity complex used for albumin binding, so it is generally used in research examining shorter-duration receptor activity and pulsatile signaling behavior.

Mechanism of Action & Applications

CJC-1295 (No DAC) is studied for agonist activity at the GHRH receptor. In laboratory research, this makes it useful for examining pituitary signaling, pulsatile growth hormone release dynamics, receptor activation patterns, and the differences between shorter-acting GHRH analogues and longer-acting albumin-binding designs. It is commonly used in studies involving GHRH receptor biology, endocrine signaling, peptide half-life comparisons, and growth hormone pathway research.

Research History

CJC-1295 (No DAC) developed from efforts to modify the native GHRH(1-29) sequence to improve receptor activity and stability while preserving a shorter-acting signaling profile than DAC-linked analogues. In published and reference chemistry sources, it is widely associated with Modified GRF (1-29), which is distinct from CJC-1295 with DAC.

Chemical Information

CAS Number

863288-34-0

Molecular Formula

C₁₅₂H₂₅₂N₄₄O₄₂

Molecular Weight

3,367.9 g/mol

PubChem ID

91972073

Compound

CJC-1295 (No DAC)

Selected quantity

10 MG per vial

Research area

Musculoskeletal & Growth

Intended use

Laboratory research only

Laboratory storage & handling

Form

Lyophilized powder

Short-term

2–8 °C (refrigerated)

Long-term

−20 °C (frozen)

Container

Use the supplied container and follow its label

Lot-specific stability

Not established on this product page

Reconstitution

Consult the applicable research protocol and available lot record

For research use only. Not for human or veterinary use.

A certificate for CJC-1295 (No DAC) 10 MG has not been published yet. Records are published per lot as they are received; a missing record is not a test result.

Use the lot number on your vial to locate the corresponding certificate once it is available, or contact support for batch documentation.

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