Melanotan I

Melanotan I Overview

Melanotan I, also known as afamelanotide or NDP-α-MSH, is an α-MSH analogue studied in research involving melanocortin signaling. In laboratory settings, it is used to examine how melanocortin receptor activity affects pigment-related cellular responses and broader melanocortin pathway biology.

Mechanism of Action & Applications

Melanotan I is studied for agonist activity at melanocortin receptors, with predominant activity described at MC1R. In research models, this makes it useful for examining melanogenesis-related signaling, receptor pharmacology, redox-associated melanocortin biology, and broader peptide-receptor interactions within the melanocortin system.

Research History

Melanotan I emerged from efforts to develop stable α-MSH analogues with longer-lasting melanocortin receptor activity than native hormone signaling. Earlier published work in the 1990s examined Melanotan I in biologic systems, and later development continued under the name afamelanotide.

Chemical Information

CAS Number

75921-69-6

Molecular Formula

C₇₈H₁₁₁N₂₁O₁₉

Molecular Weight

1,646.85 g/mol

PubChem ID

16197727

Compound

Melanotan I

Selected quantity

10 MG per vial

Research area

Reproductive & Hormonal

Intended use

Laboratory research only

Laboratory storage & handling

Form

Lyophilized powder

Short-term

2–8 °C (refrigerated)

Long-term

−20 °C (frozen)

Container

Use the supplied container and follow its label

Lot-specific stability

Not established on this product page

Reconstitution

Consult the applicable research protocol and available lot record

For research use only. Not for human or veterinary use.

A certificate for Melanotan I 10 MG has not been published yet. Records are published per lot as they are received; a missing record is not a test result.

Use the lot number on your vial to locate the corresponding certificate once it is available, or contact support for batch documentation.

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