P1-2 TZ

P1-2 TZ Overview

P1-2 TZ is a dual-receptor peptide studied for activity across GIP and GLP-1 pathways. In research settings, it is used to examine how these two receptor systems work together and how combined receptor activity influences broader metabolic and endocrine signaling. P1-2 TZ has been described in the literature as an acylated peptide engineered to activate both the GIP and GLP-1 receptors.

Mechanism of Action & Applications

P1-2 TZ is studied as a dual agonist at the GIP and GLP-1 receptors. This receptor profile allows researchers to examine how simultaneous activation of incretin-related pathways affects intracellular signaling, hormone pathway coordination, and broader metabolic system responses. Published mechanistic work also describes P1-2 TZ as having stronger relative activity at the GIP receptor and biased signaling behavior at the GLP-1 receptor, which makes it a useful compound for studying receptor-selective signaling and dual-incretin pathway biology. It is commonly used in research involving incretin receptor biology, metabolic signaling, endocrine regulation, and multi-pathway peptide signaling.

Research History

P1-2 TZ builds on earlier incretin research that first focused on GLP-1 receptor agonists and later expanded into compounds designed to engage both GIP and GLP-1 receptors. This progression led to dual-agonist peptides like P1-2 TZ, which are studied for more integrated pathway research involving incretin signaling and metabolic system coordination.

Chemical Information

CAS Number

2023788-19-2

Molecular Formula

C₂₂₅H₃₄₈N₄₈O₆₈

Molecular Weight

4,813.45 g/mol

PubChem ID

166567236

Compound

P1-2 TZ

Selected quantity

30 MG per vial

Research area

Metabolic & Endocrine

Intended use

Laboratory research only

Laboratory storage & handling

Form

Lyophilized powder

Short-term

2–8 °C (refrigerated)

Long-term

−20 °C (frozen)

Container

Use the supplied container and follow its label

Lot-specific stability

Not established on this product page

Reconstitution

Consult the applicable research protocol and available lot record

For research use only. Not for human or veterinary use.

The certificate below belongs to P1-2 TZ 30 MG, lot P1P-TZ30-001. Match the lot number on your vial to the record.

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