SNAP-8

SNAP-8 Overview

SNAP-8, also known as acetyl octapeptide-3, is an eight-amino-acid peptide studied in research involving SNARE-complex biology and peptide-mediated cellular signaling. It is commonly described as an extended analogue of argireline-type peptides and is used in laboratory settings to examine how short peptides may interact with protein machinery involved in vesicle fusion and signal transmission.

Mechanism of Action & Applications

SNAP-8 is studied for how it mimics part of the N-terminal region of SNAP-25 and interferes with SNARE complex assembly. In laboratory research, this makes it useful for examining vesicle fusion signaling, neurotransmitter-release mechanisms, peptide-protein interaction models, and broader cell-communication pathways linked to SNARE-mediated activity.

Research History

SNAP-8 emerged from earlier work on acetyl hexapeptide analogues and related cosmetic-peptide research, where extending the peptide sequence was explored as a way to study stronger or more stable interaction with SNARE-related signaling systems. Later reviews and analytical studies continued to describe SNAP-8 as an acetyl octapeptide used in research involving peptide mechanism, formulation analysis, and SNARE-complex modulation.

Chemical Information

CAS Number

868844-74-0

Molecular Formula

C₄₁H₇₀N₁₆O₁₆S

Molecular Weight

1,075.16 g/mol

PubChem ID

86080331