Semax

Semax Overview

Semax is a heptapeptide analogue of the ACTH(4-10) fragment with the sequence Met-Glu-His-Phe-Pro-Gly-Pro. In research settings, it is studied in neurobiology and peptide-signaling models involving central nervous system regulation, neurotrophin-associated activity, and stress-response pathway biology.

Mechanism of Action & Applications

Semax is studied for how it influences neurotrophin-related signaling and broader peptide-regulated nervous system activity. Published research and reagent references describe it as affecting BDNF and TrkB expression and activity in experimental systems, while other literature has explored possible interactions with melanocortin receptors and peptide-degrading enzymes. In laboratory research, this makes it useful for examining neurotrophic signaling, neuroendocrine pathway activity, stress-response biology, and peptide-mediated cellular regulation.

Research History

Semax first appeared in the scientific literature in the early 1990s as a modified ACTH fragment developed for central nervous system research. Later studies expanded into gene-expression, neurotrophin, and peptide-signaling models, helping establish Semax as a commonly referenced compound in neurobiology-focused research.

Chemical Information

CAS Number

80714-61-0

Molecular Formula

C₃₇H₅₁N₉O₁₀S

Molecular Weight

813.92 g/mol

PubChem ID

122178

Compound

Semax

Selected quantity

10 MG per vial

Research area

Neuropeptides & Immunology

Intended use

Laboratory research only

Laboratory storage & handling

Form

Lyophilized powder

Short-term

2–8 °C (refrigerated)

Long-term

−20 °C (frozen)

Container

Use the supplied container and follow its label

Lot-specific stability

Not established on this product page

Reconstitution

Consult the applicable research protocol and available lot record

For research use only. Not for human or veterinary use.

A certificate for Semax 10 MG has not been published yet. Records are published per lot as they are received; a missing record is not a test result.

Use the lot number on your vial to locate the corresponding certificate once it is available, or contact support for batch documentation.

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