NAD+
A coenzyme essential to cellular metabolism, studied in research on sirtuin activation, DNA repair mechanisms, and mitochondrial bioenergetics. It plays a central role in laboratory investigations of cellular aging, metabolic flux, and redox-dependent signaling pathways.
NAD+ Overview
NAD+, or nicotinamide adenine dinucleotide, is a coenzyme found in all living cells and is central to many metabolic processes. In research settings, it is studied for its role in energy production, electron transfer, and broader cellular systems involved in mitochondrial activity, redox regulation, and stress-response biology.
Mechanism of Action & Applications
NAD+ is studied for how it functions as an electron carrier in oxidation-reduction reactions and as a substrate for enzymes such as sirtuins, PARPs, and CD38. In laboratory research, this makes it useful for examining mitochondrial energy metabolism, DNA repair-related signaling, cellular aging pathways, oxidative stress responses, and broader metabolic regulation. It is commonly used in studies involving neurobiology, longevity-related signaling, and cellular resilience models.
Research History
NAD+ has been studied for more than a century and remains one of the most important molecules in biochemical research. Early work established its role in redox chemistry and cellular metabolism, while later studies expanded into its involvement in mitochondrial biology, enzyme regulation, and age-related cellular signaling pathways.
Chemical Information
- CAS Number
- 53-84-9
- Molecular Formula
- C21H27N7O14P2
- Molecular Weight
- 663.43 g/mol
- PubChem ID
- 5892
For research use only. Not for human or veterinary use. Detailed storage guidelines →
Researcher Reviews
