SLU-PP-332
A research compound studied for activity at estrogen-related receptors (ERRs), used in investigations of exercise-mimetic and metabolic pathway signaling. It is of particular interest in studies examining how ERR activation influences mitochondrial biogenesis and oxidative metabolism.
SLU-PP-332 Overview
SLU-PP-332 is a research compound studied for activity across the estrogen-related receptor family, including ERRα, ERRβ, and ERRγ. In laboratory settings, it is used to examine how ERR signaling influences mitochondrial biology, oxidative metabolism, and transcriptional programs linked to cellular energy use.
Mechanism of Action & Applications
SLU-PP-332 is studied as a pan ERR agonist with reported activity at ERRα, ERRβ, and ERRγ, with the strongest activity observed at ERRα in published sources. In research models, this makes it useful for examining receptor-driven transcription, mitochondrial respiration, oxidative phosphorylation, fatty acid oxidation, and broader cellular energy regulation. It is commonly used in studies involving ERR receptor biology, exercise-mimetic signaling, metabolic pathway coordination, and mitochondrial function.
Research History
SLU-PP-332 emerged from medicinal chemistry efforts to develop potent agonists of the estrogen-related receptor family. Published work in 2023 described it as a pan-ERR agonist and evaluated its pharmacologic activity in experimental systems, and subsequent studies have continued to examine its metabolism, analytical characterization, and structure-activity relationships.
Chemical Information
- CAS Number
- 303760-60-3
- Molecular Formula
- C18H14N2O2
- Molecular Weight
- 290.32 g/mol
- PubChem ID
- 5404083
For research use only. Not for human or veterinary use. Detailed storage guidelines →
Researcher Reviews
