PT-141
A cyclic melanocortin receptor agonist derived from Melanotan II, studied in research on central nervous system signaling pathways related to sexual function. Unlike PDE5-targeting compounds, it acts through MC3R/MC4R receptor activation in the hypothalamus.
PT-141 Overview
PT-141, also known as bremelanotide, is a cyclic peptide analogue derived from melanocortin-related peptide research. In laboratory settings, it is studied for its activity within the melanocortin receptor system and for how this receptor signaling influences broader neuroendocrine pathway biology.
Mechanism of Action & Applications
PT-141 is studied for agonist activity at melanocortin receptors, especially MC3R and MC4R. In research models, this makes it useful for examining melanocortin receptor pharmacology, central signaling pathways, peptide-receptor interactions, and broader neuroendocrine signaling dynamics.
Research History
PT-141 emerged from earlier melanocortin peptide research and is commonly described as a metabolite or derivative related to Melanotan II. Over time, it became a distinct research compound within the melanocortin field, with later development and characterization under the name bremelanotide.
Chemical Information
- CAS Number
- 189691-06-3
- Molecular Formula
- C50H68N14O10
- Molecular Weight
- 1,025.2 g/mol
- PubChem ID
- 9941379
For research use only. Not for human or veterinary use. Detailed storage guidelines →
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