Melanotan II

Melanotan II Overview

Melanotan II is a cyclic peptide analogue of α-melanocyte-stimulating hormone. In research settings, it is studied for its activity across melanocortin receptor systems, particularly in models examining pigmentation signaling, central melanocortin biology, and broader peptide-receptor interactions.

Mechanism of Action & Applications

Melanotan II is studied for agonist activity at melanocortin receptors, including MC1R and other receptor subtypes within the melanocortin family. In laboratory research, this makes it useful for examining melanogenesis-related signaling, receptor pharmacology, neuroendocrine pathway activity, and broader melanocortin system behavior. It is commonly used in studies involving pigmentation biology, peptide-receptor signaling, and melanocortin-mediated cellular responses.

Research History

Melanotan II developed from earlier work on α-MSH analogues designed to create more stable and potent melanocortin receptor ligands. Research expanded from pigmentation-focused models into broader studies of melanocortin signaling, where Melanotan II became a commonly referenced peptide in preclinical receptor and pathway research.

Chemical Information

CAS Number

121062-08-6

Molecular Formula

C₅₀H₆₉N₁₅O₉

Molecular Weight

1,024.2 g/mol

PubChem ID

92432

Compound

Melanotan II

Selected quantity

10 MG per vial

Research area

Reproductive & Hormonal

Intended use

Laboratory research only

Laboratory storage & handling

Form

Lyophilized powder

Short-term

2–8 °C (refrigerated)

Long-term

−20 °C (frozen)

Container

Use the supplied container and follow its label

Lot-specific stability

Not established on this product page

Reconstitution

Consult the applicable research protocol and available lot record

For research use only. Not for human or veterinary use.

The certificate below belongs to Melanotan II 10 MG, lot P1P-MT210-001. Match the lot number on your vial to the record.

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