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Neuropeptides & Immunology

KPV

$60Per vial

A tripeptide derived from alpha-MSH, studied in laboratory research on immune modulation, inflammatory signaling, and NF-kB pathway activity. It is particularly useful in research examining anti-inflammatory peptide mechanisms and melanocortin receptor-mediated immune responses.

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For laboratory research only. Not for human or veterinary use.

About KPV

KPV Overview

KPV, short for Lys-Pro-Val, is a three-amino-acid peptide corresponding to the C-terminal 11–13 fragment of α-melanocyte-stimulating hormone (α-MSH). In research settings, it is studied as a compact melanocortin-related peptide fragment with relevance to inflammatory signaling, epithelial response models, and mucosal pathway biology.

Mechanism of Action & Applications

KPV is studied for how it influences inflammation-related signaling at the cellular level. Published research has examined KPV in models involving peptide transport through PepT1, epithelial inflammatory responses, and melanocortin-associated pathway biology. This makes it useful in laboratory studies involving mucosal biology, epithelial signaling, immune-pathway research, and broader peptide-mediated inflammatory response models.

Research History

Research interest in KPV grew from work on α-MSH and related melanocortin peptides, where investigators identified the Lys-Pro-Val sequence as an important C-terminal fragment for studying inflammation-related peptide activity. Later studies expanded into epithelial, intestinal, and transport-related models, helping establish KPV as a distinct research peptide rather than only a fragment discussed within α-MSH literature.

Chemical Information

CAS Number
67727-97-3
Molecular Formula
C16H30N4O4
Molecular Weight
342.43 g/mol
PubChem ID
125672

Researcher Reviews