Cagrilintide

Cagrilintide Overview

Cagrilintide is a long-acting peptide analogue of amylin studied in metabolic research. In laboratory and clinical research settings, it is used to examine amylin-related signaling and how this pathway interacts with broader metabolic regulation systems.

Mechanism of Action & Applications

Cagrilintide is studied for agonist activity at amylin and calcitonin-family receptor systems. Research has examined how this receptor activity influences downstream signaling involved in metabolic regulation, making it useful in studies of amylin biology, receptor pharmacology, and multi-pathway metabolic signaling. More recent structural work has also described how cagrilintide engages these receptors through an amylin-like binding mode while producing distinct receptor conformations and dynamics.

Research History

Cagrilintide emerged from efforts to develop a longer-acting amylin analogue with improved stability and sustained receptor activity. Published medicinal chemistry work in 2021 described its development as a stable, lipidated long-acting amylin analogue, and later studies further characterized its receptor activity and structural behavior.

Chemical Information

CAS Number

1415456-99-3

Molecular Formula

C₁₉₄H₃₁₂N₅₄O₅₉S₂

Molecular Weight

4,409 g/mol

PubChem ID

167312356

Compound

Cagrilintide

Selected quantity

10 MG per vial

Research area

Metabolic & Endocrine

Intended use

Laboratory research only

Laboratory storage & handling

Form

Lyophilized powder

Short-term

2–8 °C (refrigerated)

Long-term

−20 °C (frozen)

Container

Use the supplied container and follow its label

Lot-specific stability

Not established on this product page

Reconstitution

Consult the applicable research protocol and available lot record

For research use only. Not for human or veterinary use.

The certificate below belongs to Cagrilintide 10 MG, lot P1P-CAG10-001. Match the lot number on your vial to the record.

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